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KMID : 1007420060040020056
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Mood and Emotion
2006 Volume.4 No. 2 p.56 ~ p.61
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Power Spectral Analysis of Resting EEG in Unmedicated Major Depressive Disorder
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Lee Jun-Seok
Jung Kyung-Hi
Yang Byung-Hwan
Park Soo-Hyungd
Lee Seung-Hwan
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Abstract
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Objectives：The present study analyzed EEG spectral power in depressed patients and healthy controls.
Methods：The subjects in this study were 11 non-depressed, age matched controls, and in 11 unmedicated unipolar depressed patients. EEG data were obtained from each participant during five minute resting baseline periods with eyes closed and then analyzed with spectral analysis. EEG absolute power and relative power were calculated for the delta,
theta, alpha and beta activity.
Results：Compared with control subjects, depressed patients had lower alpha in both temporal areas (T3, T4) and lower theta in right temporal area (T4)(p<0.05). Conclusion：Major depressive disorder subjects showed difference of brain activity in temporal areas. This findings suggest that temporal area plsys an important role in major depression.
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KEYWORD
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EEG, Spectral Analysis, Major Depressive Disorder
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